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Courses

Course descriptions

 

See also the listings for the following courses offered by more than one department or faculty which may be taken as options INT D 409 and 491 (research project courses for medical laboratory science students).

100-400 level Undergraduate courses

400/500 split level undergraduate/graduate courses

500-600 level Graduate courses


Undergraduate Courses


MMI 133
Medical microbiology for health care professionals
*3 (fi6) (Fall Term, 3-0-0)

Introductory course in medical microbiology designed for students enrolled in health care related programs. The course begins with basic information on microorganisms (bacteria, viruses, fungi, parasites and prions), the immune system, infection control, transmission of infection, epidemiology, antimicrobials, disinfection and sterilization. The later part of the course concentrates on infectious diseases caused by pathogenic microorganisms.

Coordinator: Dr. Judy Gnarpe @ 492-2302

 

IMIN 200
Infection and immunity
*3 (fi 6) (Winter term, 3-0-0)

Introduces the principles and mechanisms of immunity in eukaryotes. Provides an overview of the major groups of infectious agents (virus, bacteria, parasites) and examines selected microorganisms within the context of the host response to pathogens and pathogen evasion strategies. Pre- or corequisites: BIOCH 200 or BIOCH 203 or 220 and MICRB 265. May not be taken for credit if credit already obtained in MICRB 295.

Coordinator: Dr. Katherine Magor @ 492-5498

 

IMIN 324
Basic Virology
*3 (fi 6) (Fall term, 3-0-0)

An introduction to the structure, replication, and taxonomy of bacteriophages, plant, insect, and animal viruses. Their role in disease and methods of control and detection is also discussed. (Offered jointly by the Departments of Biological Sciences and of Medical Microbiology and Immunology).

Prerequisite: BIOL 107, IMIN 200 and BIOCH 205. May not be taken for credit if credit already obtained in INT D 224.

Co requisite: BIOL 201 or 207. Credit may be obtained in only one of MICRB 224 or MMI 224 or INT D 224.
Note: May not be taken for credit if credit already obtained in BIOCH 450.

Coordinator: Dr. James Smiley @ 492-4070

 

IMIN 371
Introduction to Immunology
*3 (fi 6) (Fall term, 3-0-0)

Survey course introducing the student to immunological concepts. Topics include the clonal selection theory, antibody structure and specificity, genetic basis of immune diversity, antibody-antigen reactions, cell interactions in immune responses, the molecular basis of non-self recognition, MHC molecules and transplantation, tolerance, effector mechanism of immunity, hypersensitivity and immunodeficiency. (Offered jointly by the Department of Biological Sciences and the Department of Medical Microbiology and Immunology).

Prerequisites: BIOCH 200 or 205, BIOL 207, and IMIN 200.

Note: May not be taken for credit if credit already obtained in INT D 371.

Coordinator: Dr. Rob Ingham @ 780-248-1980

 

IMIN 372
Research Techniques in Immunology
*3 (fi 6) (Winter term,1-0-3)

A lecture and laboratory course covering theory and practice behind selected immunological techniques. Techniques covered may include: lymphocyte isolation, flow cytometry, mixed lymphocyte reactions, immunocytochemistry, immunoprecipitation, ELISA, western blotting, expression cloning and monoclonal antibody technology. Labs will sometimes require students to return the next day to check on plates or cultures. (Offered jointly by the Departments of Biological Sciences and Medical Microbiology and Immunology). (Biological Sciences)

Prerequisite: IMIN 371.

Note: May not be taken for credit if credit already obtained in INT D 372.

Coordinators: Dr. Katherine Magor @ 492-5498 & Dr. Bradley Magor @ 492-9234

 

MMI 351
Bacterial Pathogenesis
*3 (fi 6) (Winter term, 3-0-0)

Medically important bacteria, how they cause disease and the body's immune response to bacteria. Lectures will systematically discuss the organisms and describe their distinctive as well as their common features of structure and pathogenicity.

Prerequisites: MICRB 265 and either MICRB 295 and IMIN 200.

Note: May not be taken for credit if credit already obtained in MLSCI 242 and MLSCI 243.

Coordinator: Dr. Kim Ellison @ 492-0933

 

MMI 352
Microbial Pathogenesis
*3 (fi 6) (Winter term, 0-0-4)

This laboratory course will emphasize development of skills and knowledge for the safe handling of infectious microorganisms and will examine some of the molecular mechanisms of microbial virulence.

Prerequisite or corequisite: MMI 351 or MLSCI 242 and 243 or consent of the Department.

Note: May not be taken for credit if credit already obtained in MMID 240 or 241 or 350, or in MMI 240 or 241 or 350.

Coordinator: Dr. Kim Ellison @ 492-0933

 

MMI 391
Current Methods in Molecular Biology
*3 (fi 6) (Fall term, 0-0-8)

This laboratory course will introduce the student to common techniques in molecular biology. Through a series of experiments, students will clone and express the genes for bioluminescence from the lightemitting bacterium Vibrio fischeri. Technical skills will include: preparation and quantification of genomic and plasmid DNAs, screening a genomic library, restriction mapping, amplification of DNA fragments using the polymerase chain reaction, Southern blotting, expression and purification of proteins, and detection of proteins by Western blotting.

Prerequisites: IMIN 200 and departmental consent. Priority given to Honors students in the IMIN program. Credit may be obtained for only one of BIOL 391, IMIN 391 or MMI 391.

Coordinator: Dr. Kim Ellison @ 492-0933

 

MMI 426
Medical Parasitology
*3 (fi 6) (Fall term, 3-0-3)

A survey of the protozoan and metazoan parasites of man. Emphasis will be placed on biology epidemiology clinical presentation and methods for detection and identification as well as global impact of parasitic diseases in today's world.

Prerequisites: MLSCI 242 and 243, consent of Department.

Coordinator: Dr. Kinga Kowalewska-Grochowska @ 492-8998


MMI 498
Research Project in Infection and Immunity
*3 (fi 6) (Fall or Winter term, 0-0-6)

Directed research on a specific topic in medical microbiology or immunology in the laboratory of a faculty member in the department. Can be taken for credit more than once. An oral presentation on the research project is required for completion of the course.

Pre- or corequisites: INT D 370 or 371 or INT D 452 or MMI 351 and/or consent of Department.

Coordinator: Dr. Troy Baldwin @ 492-7553

MMI 499
Independent Research in Infection and Immunity
*3 (fi 12) (Fall and Winter term, 0-0-6)

Directed research project in the laboratory of an academic staff member of the Department of Medical Microbiology and Immunology. An oral presentation and a written report on the research project is required for completion of the course.

Pre- or corequisites: INT D 370 or 371 or INT D 452 or MMI 351 and/or consent of Department.

Coordinator: Dr. Troy Baldwin @ 492-7553

 


Split undergraduate and graduate level courses


400/500 level courses can be taken by both undergraduate and graduate students, who must register at the 400 and 500 level, respectively. Graduate students typically have to add a special component beyond what all students cover.

 

MMI 405/MMI 505

Advanced Microbial Pathogenicity

*3 (fi 6) (Fall term, 3-0-0)

Selected topics regarding the production of disease by bacterial pathogens, with special emphasis on the biochemical, immunological, and physiological properties of the host and microbe that account for the pathological process. Contemporary concepts will be explored by means of lectures and class discussion of recent papers that illustrate particular examples of each concept.

For graduate students (MMI 505) lectures and seminars are the same as MMI 405, but there will be an additional requirement of a written research proposal.

Prerequisites: BIOCH 200 and  MMI 351 or MLSCI 242 and 243 or consent of the department.

Note: MMI 505 may not be taken for credit if credit has already been obtained in MMI 405.

Coordinator: Dr. Bart Hazes @ 492-0042

MMI 436/MED 536
Inflammation
*3 (fi 6) (Fall term, 3-0-0)

This course will introduce the student to inflammation and its role in a range of diseases. An overview is provided on acute and chronic inflammation, inflammatory cells (neutrophils, eosinophils, macrophages, mast cells, and structural cells), inflammatory mediators, asthma and allergy, and the danger hypothesis in association with the inflammasome. The syllabus includes a mix of lectures and current topic discussion for students to present recent advances in inflammation.

Prerequisites: IMIN 371 or instructor consent.

Coordinator: Dr. Paige Lacy @ 492-6085

IMIN 410/MMI 510
Bioinformatics for molecular biologists
*3 (fi 6)(Winter term, 3-0-1)

The course will introduce students to common and advanced methods in bioinformatics, in a mix of lectures and hands-on computer sessions. The student will solve realistic biological questions in the areas of sequence analysis, distant homology detection, phylogeny, correlating sequence to structure, protein structure analysis, genomics, and proteomics. The student will obtain a thorough understanding of bioinformatics methods but the focus is on application of methods in the context of molecular biology research rather than studying details of the algorithms or computer programming.

Prerequisites: Completion of IMIN third year, enrollment in a graduate program, or department consent. Priority given to students in the IMIN program and MMI graduate students.

Coordinator: Dr. Bart Hazes @ 492-0042

 

MMI 415/MMI 515
Mechanisms of Pathogenicity II
*3 (fi 6) (Winter term, 3-0-0)

Mechanisms of viral pathogenesis, with an emphasis on how different viruses modulate the innate and adaptive immune systems to their advantage to avoid detection and elimination and the relevance of viruses in oncogenesis. Prerequisites: BIOCH 200, IMIN 324 and IMIN 371, or consent of the Department.

Coordinator: Dr. Maya Shmulevitz @ 492-0623

 

MMI 445/545
Clinical Microbiology and Human Health
*3 (fi 6) (Winter term, 3-0-0)

This course will focus on the interactions between clinically relevant microorganisms and the host. Topics include important issues and contemporary problems in clinical microbiology regarding infectious diseases relevant to health care. Aspects that will be studied are: pathogenesis, epidemiology, immune responses, treatment and infection control. Recent advances in vaccines, laboratory diagnosis and techniques will be included.

Prerequisites: MMI 133 or MLSCI 242 and MLSCI 243 or IMIN 200 or MICRO 265 or consent of department

Coordinator: Dr. Judy Gnarpe @ 492-2302

 

IMIN 452/MMI 552
Advanced Immunology
*3 (fi 6) (Winter term, 3-1s-0)

A lecture course on the detailed mechanisms of the immune system, describing recent discoveries in cellular and molecular immunology. Topics include mechanisms of T-cell receptor selection, antigen processing, activation of B and T lymphocytes, cellular collaboration, negative and positive regulatory mechanisms in immunity, transplantation, cytokine actions and interactions, autoimmunity. Interaction between immune systems and pathogens, and immunogenetics. (Offered jointly by the Department of Biological Sciences and the Department of Medical Microbiology and Immunology).

Prerequisites: BIOCH 203 and 205 and IMIN 371.

Note: May not be taken for credit if credit already obtained in INT D 452.

Coordinator:Dr. Troy Baldwin @ 492-7553

MMI 490/590
Advanced Techniques in Microbiology and Immunology
*3 (fi 6) (either term, 0-0-8)


This lab-based course will introduce students to advanced molecular techniques for the examination of host-microbial interactions. Students will be introduced to the principles and applications of molecular and diagnostic techniques for the characterization of interactions between host cells and microbial pathogens. Key techniques include flow cytometry, fluorescence imaging, high-throughput RNA interference assays and high-content imaging.
Prerequisites: IMIN 200 and IMIN 371.

MMI 590
Upon completion, students will be required to design a proposal for the integration of course techniques with their thesis research projects. Prerequisite: consent of department. Credit cannot be given for 590 if students have already received credit for 490.

Coordinator: Dr. Edan Foley @ 492-2303

 

 


Graduate Courses


 

MMI 512
Special Projects
*3 (fi 6) (Fall or Winter term, 0-0-3)

 

MMI 501
Seminar in Medical Microbiology and Immunology
*3 (fi 6) (Fall or Winter term, 0-3s-0)

The student will prepare a seminar on an assigned topic in medical microbiology or immunology. Evaluation will focus on presentation, content, discussion of other student seminars, and proficiency in chairing other presentations. Required of all graduate students in medical microbiology and immunology.

Note: Open to graduate students in Medical Microbiology and Immunology only.

Coordinator: Dr. Deborah Burshtyn @ 492-0646

 

MMI 605
Current Topics in Infection and Immunity
*3 (fi 6) (fall, 0-4s-0)

Selected topics in infections and immunity are explored in depth through evaluation of the primary research literature. Emphasis is on the molecular and cellular mechanisms underlying pathogenesis, host resistance, and immune regulation. Information is provided through selected readings and student seminar presentations. The primary objective is to introduce students to current research topics in infection and immunity, and develop their ability to critically evaluate, organize, and present scientific information.

Coordinator: Dr James Smiley @ 492-4070

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